Open AccessNephrogenic systemic fibrosis (NSF) and gadolinium-based contrast media
Author(s) -
Patrick Ngoya,
Zakariya Vawda,
Jan Lotz
Publication year - 2013
Publication title -
sa journal of radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.18
H-Index - 3
eISSN - 2078-6778
pISSN - 1027-202X
DOI - 10.4102/sajr.v17i3.277
Subject(s) - nephrogenic systemic fibrosis , medicine , fibrosis , gadolinium , pathology , radiology , magnetic resonance imaging , materials science , metallurgy
Nephrogenic systemic fibrosis (NSF), unknown before March 1997 and first described in 2000, is a systemic disorder characterised by widespread tissue fibrosis. The first known case occurred in 1997, after the use of gadolinium-based contrast agents (GBCAs) at high doses in patients with renal failure had become routine. An overwhelming majority occurred within weeks to months after injection of a GBCA. This note comprises guidelines on the prevention of NSF