Open AccessTardive dyskinesia on clozapine: A case report
Author(s) -
Laila Asmal
Publication year - 2009
Publication title -
south african journal of psychiatry
Language(s) - English
Resource type - Journals
eISSN - 2078-6786
pISSN - 1608-9685
DOI - 10.4102/sajpsychiatry.v15i1.169
Subject(s) - tardive dyskinesia , clozapine , medicine , antipsychotic , dyskinesia , atypical antipsychotic , antipsychotic drug , pediatrics , schizophrenia (object oriented programming) , psychiatry , disease , parkinson's disease
Antipsychotic-induced tardive dyskinesia is a potentially irremediable and debilitating condition with the onset most commonly associated with the use of first-generation antipsychotics. The development of tardive dyskinesia on clozapine, a second-generation antipsychotic, is uncommon, and the drug is therefore a treatment option for those patients who develop the syndrome following treatment with first- generation agents. I report on the case of a 27-year-old man who developed severe tardive dyskinesia following initiation of clozapine treatment. To the best of my knowledge, this is the first case of tardive dyskinesia associated with clozapine use reported in South Africa