Open AccessMechanisms of antibiotic resistance in Haemophilus parainfluenzae
Author(s) -
Regina E. Abotsi,
Usha Govinden,
Sabiha Y. Essack
Publication year - 2017
Publication title -
southern african journal of infectious diseases
Language(s) - English
Resource type - Journals
eISSN - 2313-1810
pISSN - 2312-0053
DOI - 10.4102/sajid.v32i3.49
Subject(s) - haemophilus parainfluenzae , fastidious organism , haemophilus , microbiology and biotechnology , antibiotic resistance , antibiotics , eikenella corrodens , endocarditis , bacteremia , biology , medical microbiology , medicine , bacteria , haemophilus influenzae , genetics
Haemophilus parainfluenzae is part of the HACEK group of fastidious bacteria commonly implicated in endocarditis and bacteremia. Previously considered as a normal respiratory, oral and sometimes genitourinary commensal, it has been recognised as a pathogen that can cause life-threatening infections in both immunocompromised and healthy individuals. It has also been reported as a bacterium that can harbor transferable antibiotic resistance genes. This paper presents a literature review on the molecular mechanisms of resistance of H. parainfluenzae to commonly prescribed antibiotics and discusses areas for further research.