Open AccessCorrelates of bacterial ulcers and acute HSV-2 infection among men with genital ulcer disease in South Africa: age, recent sexual behaviours, and HIVi,ii
Author(s) -
Jami S. Leichliter,
David A. Lewis
Publication year - 2016
Publication title -
southern african journal of infectious diseases
Language(s) - English
Resource type - Journals
eISSN - 2313-1810
pISSN - 2312-0053
DOI - 10.4102/sajid.v31i2.92
Subject(s) - haemophilus ducreyi , medicine , chlamydia trachomatis , genital ulcer , treponema , chlamydia , sex organ , sexually transmitted disease , human immunodeficiency virus (hiv) , immunology , syphilis , haemophilus influenzae , microbiology and biotechnology , antibiotics , biology , pasteurellaceae , genetics
Data from baseline surveys and STI/HIV laboratory tests (n=615 men) were used to examine correlates of bacterial ulcers (Treponema pallidum, Haemophilus ducreyi, or Chlamydia trachomatis L1-L3 detected in ulcers) and acute HSV-2 ulcers (HSV-2 positive ulcer specimen, HSV-2 sero-negative, and negative for bacterial pathogens) versus recurrent HSV-2 ulcers (seropositive), separately. Men with bacterial ulcers had larger ulcers compared to men with recurrent HSV-2 ulcers, but were less likely to be HIV-positive; whereas, men with acute HSV-2 ulcers were younger with fewer partners. Acute HIV was higher among men with bacterial and acute HSV-2 ulcers; however, this difference was not statistically significant.