Open AccessProgressive HIV infection in the presence of a raised CD4+ count: HIV/HTLV-1 co-infection
Author(s) -
Ahmad F. Haeri Mazanderani,
Osman Ebrahim
Publication year - 2013
Publication title -
southern african journal of hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 18
eISSN - 2078-6751
pISSN - 1608-9693
DOI - 10.4102/sajhivmed.v14i2.85
Subject(s) - medicine , immunology , chemoprophylaxis , context (archaeology) , human immunodeficiency virus (hiv) , splenectomy , immune system , viral load , antiretroviral therapy , virology , spleen , paleontology , biology
There are a number of pathophysiological causes for a normal or raised CD4 count in the context of progressive HIV infection. These include various co-infections, previous splenectomy, and lymphoproliferative disorders. Such circumstances can both confound HIV diagnosis and delay initiation of chemoprophylaxis and highly active antiretroviral therapy (HAART). We describe the case of a patient co-infected with HIV and human T-cell lymphotropic virus type 1 (HTLV-1) who, prior to HAART initiation, was found to have progressive immune deficiency associated with a raised CD4 count.