Open AccessManagement of HIV-hepatitis B co-infection
Author(s) -
Marc Mendelson
Publication year - 2011
Publication title -
southern african journal of hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.859
H-Index - 18
eISSN - 2078-6751
pISSN - 1608-9693
DOI - 10.4102/sajhivmed.v12i1.209
Subject(s) - medicine , asymptomatic , hepatitis b virus , hepatitis b , antiretroviral therapy , human immunodeficiency virus (hiv) , vaccination , liver disease , disease , immunology , virology , virus , viral load
HIV-hepatitis B virus (HBV) co-infected patients are at risk of increased morbidity and mortality. Early recognition of dual infection is a critical factor in directing appropriate therapy, and HBV screening should therefore be undertaken at the time of HIV diagnosis. Vaccination against HBV should be considered for all HIV patients who are not yet infected with HBV. Antiretroviral therapy containing two antiretrovirals active against HBV should be started if the patient either has symptomatic liver disease or is asymptomatic with a CD4 count of <350 cells/µl