A new potent analgesic for chemical immobilization of gemsbok oryx gazella gazella | Zendy

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A new potent analgesic for chemical immobilization of gemsbok <i>oryx gazella</i> gazella

Author(s) -

V. De Vos

Publication year - 1978

Publication title -

koedoe

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.419

H-Index - 29

eISSN - 2071-0771

pISSN - 0075-6458

DOI - 10.4102/koedoe.v21i1.971

Subject(s) - xylazine , tranquilizer , oryx , analgesic , chemistry , sedative , pharmacology , anesthesia , medicine , biology , ketamine , ecology

The successful chemical immobilization of gemsbok Oryx gazella gazella with a new potent analgesic, R33799 (Janssen Pharmaceutica), and the major sedative xylazine hydro-chloride (Rompun; Bayer) is described. Evidence, which is presented, show that the R33799 - xylazine mixture is an improvement over previously used drug mixtures for the immobilization of gemsbok. The following optimal dosage rates and application are recommended: 10-20 ug R33 799 per kg + 100 ug xylazine per kg deep intra-muscularly. It is concluded that with the use of the above-mentioned drug mixtures and deposition site, almost predictable short induction periods of about 5 minutes or less can be achieved. High dosage levels of xylazine was found to produce a delayed or persistent somnolent state which has the disadvantage of a long and hazardous recovery phase, especially in predator prone surroundings. Results show that the action of R33799 could be effectively reversed with the usual morphine antagonists. Propionylpromazine (Combelen; Bayer) was found to be a useful post-capture tranquilizer.

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