Open AccessHIV and AIDS can result in visual impairment, therefore it is important that those who have or atrisk of contracting the disease have a basic knowledge of its ocular manifestations, so that they may seek eye care early. This study assessed the per-ceptions of a sample of senior high school students at the Capricorn district, Limpopo Province, South Africa about the ocular manifestations of HIV/AIDS and its management. Questionnaires were distributed to the students in their classrooms after school hours and upon completion were collected the same day. Data analysis revealed that 27.8% of the participants agreed that HIV/AIDS can affect the eyes. Another 27.8% responded that HIV/AIDS could cause dry eyes. Less than a third (31.4%) indicated that the disease could cause red eyes, 31.5% and 38.1% respectively indicated that HIV/AIDS could cause cancer of the eyelids and the eyeball. About half of the respondents (52%) agreed that the disease could cause swollen eyelids; while about 46% agreed that vision loss or blindness could occur in HIV/AIDS. Many (65.6%) indicated that an ophthalmologist or an optometrist should be consulted for HIV/AIDS-related eye problems and only 16.5% reported that traditional healers could be consulted. Perception about the ocular manifestations of HIV and AIDS is poor among the participants, suggesting a need for awareness campaigns and education. (S Afr Optom 2012 71(3) 117-122)