Open AccessHyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana
Author(s) -
Ellen Gobusamang,
Naledi Gape Nyepetsi,
Modisa S. Motswaledi,
Ishmael Kasvosve
Publication year - 2019
Publication title -
african journal of laboratory medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 11
eISSN - 2225-2010
pISSN - 2225-2002
DOI - 10.4102/ajlm.v8i1.786
Subject(s) - dyslipidemia , medicine , creatinine , uric acid , diabetes mellitus , type 2 diabetes mellitus , triglyceride , cholesterol , confidence interval , endocrinology , glycated hemoglobin , gastroenterology , high density lipoprotein , type 2 diabetes
Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September–December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyperuricaemia (> 400 µ mol/L) or normal serum uric acid (≤ 400 µ mol/L). We compared glycated haemoglobin, triglycerides, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, total cholesterol and serum creatinine between the two serum uric acid categories. Hyperuricaemia was detected in 28% of patients (95% confidence interval 23.1–32.9) and was associated with increased serum triglycerides, triglyceride to high-density lipoprotein-cholesterol ratio and creatinine concentration, but not with glycated haemoglobin.