Open AccessCombining Stimulants and Monoamine Oxidase Inhibitors: A Reexamination of the Literature and a Report of a New Treatment Combination
Author(s) -
Joshua A. Israel
Publication year - 2015
Publication title -
primary care companion to cns disorders/the primary care companion for cns disorders
Language(s) - English
Resource type - Journals
eISSN - 2155-7772
pISSN - 2155-7780
DOI - 10.4088/pcc.15br01836
Subject(s) - monoamine oxidase inhibitor , bupropion , tranylcypromine , stimulant , selegiline , methylphenidate , medicine , antidepressant , psychiatry , monoamine oxidase , atomoxetine , serotonin syndrome , depression (economics) , attention deficit hyperactivity disorder , psychology , anxiety , smoking cessation , enzyme , receptor , pathology , disease , parkinson's disease , serotonergic , serotonin , economics , chemistry , biochemistry , macroeconomics
This report reviews the medical literature on combining stimulants with monoamine oxidase inhibitors. A case is also presented documenting successful treatment of major depressive disorder and comorbid attention-deficit/hyperactivity disorder using the previously undocumented combination of transdermal selegiline and lisdexamfetamine. This combination should be used cautiously and with ongoing monitoring of heart rate and blood pressure.