Combining Stimulants and Monoamine Oxidase Inhibitors: A Reexamination of the Literature and a Report of a New Treatment Combination | Zendy

Joshua A. Israel | Zendy

Open Access

Combining Stimulants and Monoamine Oxidase Inhibitors: A Reexamination of the Literature and a Report of a New Treatment Combination

Author(s) -

Joshua A. Israel

Publication year - 2015

Publication title -

the primary care companion for cns disorders

Language(s) - English

Resource type - Journals

eISSN - 2155-7772

pISSN - 2155-7780

DOI - 10.4088/pcc.15br01836

Subject(s) - monoamine oxidase inhibitor , bupropion , tranylcypromine , stimulant , selegiline , methylphenidate , medicine , antidepressant , psychiatry , monoamine oxidase , atomoxetine , serotonin syndrome , depression (economics) , attention deficit hyperactivity disorder , psychology , anxiety , smoking cessation , enzyme , receptor , pathology , disease , parkinson's disease , serotonergic , serotonin , economics , chemistry , biochemistry , macroeconomics

This report reviews the medical literature on combining stimulants with monoamine oxidase inhibitors. A case is also presented documenting successful treatment of major depressive disorder and comorbid attention-deficit/hyperactivity disorder using the previously undocumented combination of transdermal selegiline and lisdexamfetamine. This combination should be used cautiously and with ongoing monitoring of heart rate and blood pressure.

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