Open AccessSulfotransferase 4A1 Haplotype 1 (SULT4A1-1) Is Associated With Decreased Hospitalization Events in Antipsychotic-Treated Patients With Schizophrenia
Author(s) -
Qian Liu,
Timothy L. Ramsey,
Herbert Y. Meltzer,
Bill W. Massey,
Saranya Padmanabhan,
Michael Brennan
Publication year - 2012
Publication title -
primary care companion to cns disorders/the primary care companion for cns disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 50
eISSN - 2155-7772
pISSN - 2155-7780
DOI - 10.4088/pcc.11m01293
Subject(s) - quetiapine , ziprasidone , olanzapine , medicine , antipsychotic , hazard ratio , haplotype , risperidone , exacerbation , psychiatry , proportional hazards model , schizophrenia (object oriented programming) , allele , genetics , biology , confidence interval , gene
To evaluate a common genetic variant, sulfotransferase 4A1 haplotype 1 (SULT4A1-1), as a predictor of hospitalization events due to the exacerbation of schizophrenia for patients treated with antipsychotic medications. Haplotypes were determined using single nucleotide polymorphism data.