Open AccessEarly- Versus Adult-Onset Schizophrenia as a Predictor of Response to Neuroscience-Informed Cognitive Training
Author(s) -
Olga Puig,
Melissa Fisher,
Rachel Loewy,
Kathleen Miley,
Ian S. Ramsay,
Cameron S. Carter,
J. Daniel Ragland,
Tara Niendam,
Sophia Vinogradov
Publication year - 2020
Publication title -
the journal of clinical psychiatry/the journal of clinical psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 207
eISSN - 1534-8628
pISSN - 0160-6689
DOI - 10.4088/jcp.18m12369
Subject(s) - schizophrenia (object oriented programming) , cognition , psychology , cognitive training , audiology , verbal learning , cognitive neuroscience , verbal memory , neuroplasticity , clinical psychology , neuroscience , psychiatry , medicine
Developmental stages characterized by greater neural plasticity might be critical periods during which the effects of cognitive training (CT) could theoretically be maximized. However, experiencing a first episode of schizophrenia during childhood or adolescence (ie, early-onset schizophrenia [EOS]) may reduce the brain's ability to benefit from CT. This study examined the effects of EOS versus onset at > 18 years of age (ie, adult-onset schizophrenia [AOS]) as a predictor of response to CT and the relationship between duration of illness and cognitive improvements.