INCREASED RISK OF LYMPHOMA IN MEN INFECTED WITH TUBERCULOSIS | Zendy

Guangliang Chen | Zendy

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INCREASED RISK OF LYMPHOMA IN MEN INFECTED WITH TUBERCULOSIS

Author(s) -

Guangliang Chen

Publication year - 2021

Publication title -

mediterranean journal of hematology and infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 31

ISSN - 2035-3006

DOI - 10.4084/mjhid.2021.053

Subject(s) - medicine , lymphoma , tuberculosis , non hodgkin's lymphoma , mycobacterium tuberculosis , risk factor , t cell lymphoma , gastroenterology , marginal zone , immunology , b cell , pathology , antibody

Purpose: To identify factors associated with lymphoma in patients with anterior Mycobacterium tuberculosis (TB). Methods: A retrospective case-control analysis was performed in a highly tuberculosis-endemic area. TB-infected patients were retrospectively identified when a history of TB exists before the diagnosis of lymphoma. Inpatients with lymphoma (n=1,057) and benign tumors (n=12,916) were consecutively enrolled at Xinjiang Medical University Cancer Hospital between January 2016 and December 2019. Results: The proportion of TB in patients with lymphoma (n=148, 14.0%) was significantly higher than that in the control (benign tumor) group (n=175, 1.4%) (p 60 years) was associated with the B-cell NHL. Conclusion: A high proportion of Mycobacterium tuberculosis infection was found in patients with lymphoma. In TB-infected patients, older age and male gender are associated with susceptibility to lymphoma, suggesting the awareness of a screening program might be useful for early detection of lymphoma.

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