Open AccessINCREASED RISK OF LYMPHOMA IN MEN INFECTED WITH TUBERCULOSIS
Author(s) -
Li Guo,
Guang-Liang Chen,
Yong Zhou,
Gui-Qin Yao,
Shuai Yang,
Dongmei Ji
Publication year - 2021
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2021.053
Subject(s) - medicine , lymphoma , tuberculosis , non hodgkin's lymphoma , mycobacterium tuberculosis , risk factor , t cell lymphoma , gastroenterology , marginal zone , immunology , b cell , pathology , antibody
Purpose: To identify factors associated with lymphoma in patients with anterior Mycobacterium tuberculosis (TB).
Methods: A retrospective case-control analysis was performed in a highly tuberculosis-endemic area. TB-infected patients were retrospectively identified when a history of TB exists before the diagnosis of lymphoma. Inpatients with lymphoma (n=1,057) and benign tumors (n=12,916) were consecutively enrolled at Xinjiang Medical University Cancer Hospital between January 2016 and December 2019.
Results: The proportion of TB in patients with lymphoma (n=148, 14.0%) was significantly higher than that in the control (benign tumor) group (n=175, 1.4%) (p 60 years) was associated with the B-cell NHL.
Conclusion: A high proportion of Mycobacterium tuberculosis infection was found in patients with lymphoma. In TB-infected patients, older age and male gender are associated with susceptibility to lymphoma, suggesting the awareness of a screening program might be useful for early detection of lymphoma.