Open AccessCYTOMEGALOVIRUS-INDUCED GASTROINTESTINAL BLEEDING AND PANCREATITIS COMPLICATING SEVERE COVID-19 PNEUMONIA: A PARADIGMATIC CASE.
Author(s) -
Giacomo Marchi,
Alice Vianello,
Ernesto Crisafulli,
Alessio Maroccia,
Stefano Francesco Crinò,
Sara Pecori,
Giulia Zamboni,
Fulvia Mazzaferri,
Evelina Tacconelli,
Domenico Girelli
Publication year - 2020
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2020.060
Subject(s) - medicine , abdominal pain , pneumonia , cytomegalovirus , pancreatitis , anorexia , diarrhea , gastrointestinal bleeding , covid-19 , duodenitis , disease , intensive care medicine , immunology , gastroenterology , viral disease , virus , infectious disease (medical specialty) , herpesviridae , gastritis , stomach
Key points:
COVID-19 is a novel pandemic disease whose pathophysiology and clinical description are still not completely defined.
Besides respiratory symptoms, gastrointestinal (GI) symptoms (especially including anorexia, diarrhea, and abdominal pain) represent the commonest clinical manifestations.
Emerging data point out that severe SARS-CoV-2 infection causes an immune dysregulation, which in turn may favor other infections.
Here we describe a patient with severe COVID-19 pneumonia who developed in the resolving phase abdominal pain associated to cytomegalovirus (CMV)-induced duodenitis with bleeding, and pancreatitis.
A high level of suspicion toward multiple infections, including CMV, should be maintained in COVID-19 patients with heterogeneous clinical manifestations.