Open Access- KAWASAKI DISEASE AS THE IMMUNE-MEDIATED ECHO OF A VIRAL INFECTION
Author(s) -
Donato Rigante
Publication year - 2020
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2020.039
Subject(s) - medicine , kawasaki disease , disease , etiology , immune system , immunology , immune dysregulation , infectious disease (medical specialty) , viral infection , genetic predisposition , virus , pathology , artery
Although etiology of Kawasaki disease remains elusive, the available evidence indicates that the primum movens might be a dysregulation of immune responses to various microbes, i.e. a kind of immune-mediated response induced by a viral infection. Even if several data might suggest that Kawasaki disease is an infection-related clinical syndrome, which can develop only in children with a predisposing genetic background, our knowledge on both the infectious agents involved and the genetic characteristics of children prone to the disease remains poor.