Open AccessThe First Case of Concomitant Mycobacterium genavense lymphadenitis and EBV-positive lymphoproliferative disorder
Author(s) -
Yusuke Ito,
Kensuke Takaoka,
Kazuhiro Toyama,
Kazuki Taoka,
Yoshitaka Wakabayashi,
Aya ShinozakiUshiku,
Aiko Okazaki,
Kinuyo Chikamatsu,
Satoshi Mitarai,
Tetsuo Ushiku,
Mineo Kurokawa
Publication year - 2020
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2020.035
Subject(s) - medicine , immunosuppression , immunology , lymphoproliferative disorders , immunodeficiency , epstein–barr virus , lymphoma , virus , virology , concomitant , immune system
This is the first case of concurrent Mycobacterium genavense lymphadenitis and Epstein-Barr virus (EBV)-positive lymphoproliferative disorder (LPD) in the same lymph node with no immunocompromised history. M. genavense infection is a rare opportunistic infection mainly for human immunodeficiency virus (HIV)-infected patients. Although no immunodeficiency was detected in our patient, our case indicates that the immunodeficiency in the background of EBV latency type III and the immunosuppression by malignant lymphoma itself might induce the M. genavense lymphadenitis. This case highly alerts clinicians the immunosuppressive state of EBV-positive LPD with latency type III even if any serological immunodeficient factors are not detected.