Open AccessAn Urologic Face of Chronic Lymphocytic Leukemia:Sequential Prostatic and Penis Localization
Author(s) -
Giovanni D’Arena,
Roberto Guariglia,
Oreste Villani,
Maria Carmen Martorelli,
Giuseppe Pietrantuono,
Giovanna Mansueto,
Giuseppe Patitucci,
Emilio Imbriani,
Tommaso Masciandaro,
Ludovica Borgia,
Giulia Vita,
Fiorella D’Auria,
Teodora Statuto,
Pellegrino Musto
Publication year - 2013
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2013.008
Subject(s) - medicine , glans penis , chronic lymphocytic leukemia , prostate , penis , urinary system , leukemia , lesion , infiltration (hvac) , pathology , disease , urology , dermatology , surgery , cancer , physics , thermodynamics
We report a patient with chronic lymphocytic leukemia (CLL) in whom a leukemic involvement of prostate and penis occurred in the advanced phase of his disease. Obstructive urinary symptoms were indicative of prostatic CLL infiltration, followed by the occurrence of an ulcerative lesion on the glans. Histologic examination confirmed the neoplastic B-cell infiltration. Both localizations responded to conventional treatments. A review of the literature confirms that leukemic involvement of the genito-urinary system is uncommon in CLL patients. However, it should be considered in CLL patients with urologic symptoms and a long history of the disease.