Open AccessSpontaneous pneumothorax in an allogeneic cell transplant recipient with invasive pulmonary aspergillosis and antecedent RSV pneumonitis
Author(s) -
Liang-Piu Koh,
Michelle Poon,
John Kit-Chung Tam,
Lynette Teo,
Li-Yang Hsu
Publication year - 2011
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2011.014
Subject(s) - medicine , antecedent (behavioral psychology) , pneumonitis , pneumothorax , aspergillosis , hypersensitivity pneumonitis , lung , pulmonary aspergillosis , immunology , pathology , surgery , psychology , developmental psychology
We report a case of invasive pulmonary aspergillosis (IPA) following respiratory syncytial virus infection in an allogeneic hematopoietic stem cell transplant (HSCT) recipient with chronic graft-versus-host disease. Delayed diagnosis of IPA resulted in the development of a pneumothorax, a rare consequence of fungal pneumonia. Respiratory virus infections are often harbingers of other infective organisms in HSCT recipients. More aggressive diagnostic investigations such as computed tomography scans of the thorax and bronchoscopy with bronchoalveolar lavage should be considered early in any HSCT patient presenting with respiratory virus pneumonia, particularly if atypical features are present or recovery is delayed.