Open AccessGLI ESOSOMI NELLA COMUNICAZIONE CELLULA-CELLULA
Author(s) -
Stefania Raimondo
Publication year - 2020
Publication title -
rendiconti. classe di scienze matematiche e naturali
Language(s) - English
Resource type - Journals
eISSN - 2384-986X
pISSN - 1974-6989
DOI - 10.4081/scie.2016.544
Subject(s) - extracellular , microbiology and biotechnology , microvesicles , vesicle , cell , intracellular , extracellular vesicle , extracellular matrix , cell type , cell signaling , multicellular organism , biology , chemistry , signal transduction , microrna , biochemistry , membrane , gene
Cell to cell communication is essential for the coordination and proper organization of different cell types in multicellular systems. Cells exchange information through a multitude of mechanisms such as secreted growth factors and chemokines, small molecules (peptides, ions, bioactive lipids and nucleotides), cell-cell contact and the secretion of extracellular matrix components. Over the last few years a new and sophisticated mechanism of cell-cell communication based on extracellular vesicles has been described. Extracellular vesicles are specialized vesicles released in the extracellular space by most of cell types, under physiological and pathological conditions. Among different extracellular vesicles subtypes, exosomes (30-100 nm) have recently received most of the attention do to their ability to be messenger in intercellular communication.