Intraventricular ciprofloxacin usage in treatment of multidrug-resistant central nervous system infections: report of four cases | Zendy

Ayşe Karaaslan | Zendy; Eda Kepenekli | Zendy; Özden TÜREL | Zendy; Demet Toprak | Zendy; Ahmet Soysal | Zendy; Mustafa Bakır | Zendy

Open Access

Intraventricular ciprofloxacin usage in treatment of multidrug-resistant central nervous system infections: report of four cases

Author(s) -

Ayşe Karaaslan,

Eda Kepenekli,

Özden TÜREL,

Demet Toprak,

Ahmet Soysal,

Mustafa Bakır

Publication year - 2014

Publication title -

pediatric reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.297

H-Index - 19

ISSN - 2036-7503

DOI - 10.4081/pr.2014.5619

Subject(s) - medicine , ciprofloxacin , multiple drug resistance , central nervous system , antibiotics , drug resistance , cerebrospinal fluid , intensive care medicine , pharmacology , microbiology and biotechnology , biology

In recent years, multidrug-resistant microorganisms appear as important nosocomial pathogens which treatment is quite difficult. As sufficient drug levels could not be achieved in cerebrospinal fluid during intravenous antibiotic therapy for central nervous system infections and due to multidrug-resistance treatment alternatives are limited. In this study, four cases of central nervous system infections due to multidrug-resistant microorganisms who were successfully treated with removal of the devices and intraventricular ciprofloxacin are presented. In conclusion, intraventricular ciprofloxacin can be used for treatment of central nervous system infections if the causative microorganism is sensitive to the drug and no other alternative therapy is available

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