Open AccessMagnetic resonance imaging and clinically controlled improvement of a combined autologous conditioned plasma combined with rh collagen type I injections in lateral epicondylitis
Author(s) -
A. W. A. Baltzer,
Martin Ostapczuk
Publication year - 2021
Publication title -
orthopedic reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.412
H-Index - 13
eISSN - 2035-8237
pISSN - 2035-8164
DOI - 10.4081/or.2021.9018
Subject(s) - epicondylitis , medicine , magnetic resonance imaging , visual analogue scale , range of motion , wrist , tennis elbow , tendon , nuclear medicine , surgery , elbow , radiology
The purpose of the study was to investigate the effect of combined autologous conditioned plasma and recombinant human collagen type I injections on lateral epicondylitis. Outcome was measured in 5 patients before the single application of ACP+rhCollagen type I (Arthrex ACP® Tendo) and after 10.60±3.58wks by means of (i) the Visual Analogue Scale for pain, (ii) range of motion for wrist extension/flexion as well as supination/pronation, and (iii) MRI-scans. VAS-scores significantly decreased from 6.40±1.14 at baseline to 1.80±2.49 at follow- up, and the effect was very large (p=0.04, dz=2.22). In addition, range of motion either improved or remained unrestricted, and MRI-scans showed healing of the extensor carpi radialis brevis tendon in most cases. A combined ACP+rhCollageninjection successfully reduces pain in lateral epicondylitis. Due to the small sample size, however, these promising preliminary results need further investigation in future research.