Open AccessHip and knee replacement in patients with ochronosis: Clinical experience and literature review
Author(s) -
Cesare Meschini,
Michele Cauteruccio,
Maria Serena Oliva,
Giuseppe Sircana,
R Vitiello,
Giuseppe Rovere,
Francesco Muratori,
Giulio Maccauro,
Antonio Ziranu
Publication year - 2020
Publication title -
orthopedic reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.412
H-Index - 13
eISSN - 2035-8237
pISSN - 2035-8164
DOI - 10.4081/or.2020.8687
Subject(s) - alkaptonuria , ochronosis , medicine , homogentisic acid , arthropathy , degenerative arthritis , surgery , osteoarthritis , dermatology , pathology , alternative medicine , biochemistry , chemistry
Patients with alkaptonuria can present ochronotic degenerative arthropathy due to the accumulation of pigments in the cartilages. Ochronotic arthropathy initially affects the spine, then there is the involvement of the other large joints, with greater frequency of the knees. In this article we will present two patients with alkaptonuria who have been effectively treated with knee and hip replacement, comparing our experience with what is available in the literature.