Alternating flexed-extended posturing in progressive supranuclear palsy | Zendy

Nobuyuki Ishii | Zendy; Hitoshi Mochizuki | Zendy

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Alternating flexed-extended posturing in progressive supranuclear palsy

Author(s) -

Nobuyuki Ishii,

Hitoshi Mochizuki

Publication year - 2019

Publication title -

neurology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.39

H-Index - 16

ISSN - 2035-8377

DOI - 10.4081/ni.2019.8257

Subject(s) - medicine , progressive supranuclear palsy , physical medicine and rehabilitation , pathology , disease

A 69-year-old man who had been bedridden in nursing home because of a 5- year history of progressive supranuclear palsy (PSP) was admitted due to aspiration pneumonia. Besides neck dystonia in extension, he showed "alternating flexed-extended posturing", in which the arm was flexed on one side and extended on the other. Magnetic resonance imaging of the brain revealed global cerebral atrophy that predominantly affected the cortex and midbrain. The mechanisms of complex posturing in late-stage PSP may sometimes be related to decortication and decerebration as well as dystonia, and "alternating flexed- extended posturing" might be one of the phenotypes of pathological progression in PSP.

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