Use of non-invasive ventilation to facilitate extubation in a patient with amyotrophic lateral sclerosis with hypercapnic respiratory failure | Zendy

Montserrat DiazAbad | Zendy; Chandana Chauhan | Zendy; Denise Epps | Zendy; James W. Russell | Zendy; Justin Kwan | Zendy

Open Access

Use of non-invasive ventilation to facilitate extubation in a patient with amyotrophic lateral sclerosis with hypercapnic respiratory failure

Author(s) -

Montserrat DiazAbad,

Chandana Chauhan,

Denise Epps,

James W. Russell,

Justin Kwan

Publication year - 2019

Publication title -

neurology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.39

H-Index - 16

ISSN - 2035-8377

DOI - 10.4081/ni.2019.8102

Subject(s) - medicine , amyotrophic lateral sclerosis , respiratory failure , pneumonia , mechanical ventilation , ventilation (architecture) , neuromuscular disease , intensive care medicine , noninvasive ventilation , aspiration pneumonia , anesthesia , disease , mechanical engineering , engineering

We present the case of a 44-year-old man with amyotrophic lateral sclerosis (ALS) intubated for hypercapnic respiratory failure and aspiration pneumonia. The patient was successfully extubated, transitioned to non-invasive ventilation and lived at home comfortably for 17 months, with good functional status for the first year. This case highlights the potential of prolonged survival post extubation in patients with advanced ALS and respiratory failure. The patient was managed post-discharge in a multidisciplinary ALS clinic by experienced neuromuscular and pulmonary specialists.

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