Open AccessDiagnostic and therapeutic aspects in patients with chronic osteomyelitis and prosthetic infections
Author(s) -
Vanessa Mary Crapanzano Minichello,
Daniela Segala,
Lorenzo Badia,
Rosario Cultrera,
Anastasio Grilli,
Leo Massari,
Carlo Contini
Publication year - 2008
Publication title -
microbiologia medica
Language(s) - English
Resource type - Journals
eISSN - 2280-6423
pISSN - 1120-0146
DOI - 10.4081/mm.2008.2594
Subject(s) - medicine , osteomyelitis , joint infections , orthopedic surgery , antibiotics , intensive care medicine , infectious disease (medical specialty) , debridement (dental) , multidisciplinary approach , antibiotic therapy , surgery , bone infection , surgical debridement , disease , arthroplasty , social science , sociology , periprosthetic , microbiology and biotechnology , biology
Management of chronic osteomyelitis and prosthetic joint infections represents an emergent problem, despite the advances in antibiotics and new operative techniques. In order to evaluate the efficacy of a multidisciplinary approach we conducted a study on twelve patients with orthopedic devices related infections attending the Institute of Infectious Diseases of the University of Ferrara from 2001 to 2006, by analyzing clinical, laboratoristic and strumental outcomes.The best results were obtained for those patients who underwent surgical treatment, including bone debridement or removal of infected devices, associated with an adequate antibiotic treatment. Moreover, encouraging results were found by analyzing the outcomes from 2 patients who underwent hyperbaric (HBO) and antibiotic therapy, as well as in patients with prosthetic-joint infections treated with antibiotics only. Our experience allows us to confirm the importance of a close interaction between infectious disease specialists, orthopaedic surgeons, radiologists, plastic surgeons, microbiologists and specialists in hyperbaric medicine in the management of bone and prosthetic joint infections