Open AccessAnalysis of metabolic networks controlled by microRNAs in zebrafish
Author(s) -
Susana Ferrando,
Sergio Bottero,
Lorenzo Gallus,
Paul Arrigo
Publication year - 2011
Publication title -
journal of biological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 6
eISSN - 2284-0230
pISSN - 1826-8838
DOI - 10.4081/jbr.2011.4482
Subject(s) - microrna , zebrafish , computational biology , biology , gene , regulation of gene expression , genetics , bioinformatics
MicroRNAs regulate gene expression at post-transcriptional level. The potential target of a miRNA can be computationally individuated, through a comparison of sequences. Here are presented the preliminary data obtained from a bioinformatic retrieval of the miRNAs involved in the regulation of the arginine metabolism in zebrafish, through the web resource MicroCosm Target (EBI). The potential "key miRNAs" individuated (miR-194b, miR-738 and miR-132*) in this pathway should be considered for an experimental validation