Open AccessEffects of Lipopolysaccharides on Activity of Mitochondrial Reductase in Rat Liver Cells
Author(s) -
S. Sesti,
G. Martino,
S. Mazzulla,
R. Chimenti
Publication year - 2003
Publication title -
journal of biological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 6
eISSN - 2284-0230
pISSN - 1826-8838
DOI - 10.4081/jbr.2003.10562
Subject(s) - bacterial outer membrane , nitric oxide , lipopolysaccharide , reductase , mitochondrion , glycolipid , bacteria , enzyme , cell , biology , biochemistry , microbiology and biotechnology , bacterial cell structure , chemistry , escherichia coli , immunology , gene , endocrinology , genetics
Lipopolysaccharides (LPS) are glycolipids found in abundance on the outer membrane of all gram-negative bacteria and have the ability to incite a vigorouse inflammatory response.They are among the agents that are able to induce changes in liver functions by production of nitric oxide (NO).The liver has the ability not only to clear LPS, but to respond energetically to LPS [1].The aim of the present study is to verify the action of LPS on activity of mitochondrial reductase on rat liver cell cultures. [...]