Open AccessEndothelial Paracrine Action
Author(s) -
D. Mancardi
Publication year - 1970
Publication title -
journal of biological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 6
eISSN - 2284-0230
pISSN - 1826-8838
DOI - 10.4081/jbr.2003.10508
Subject(s) - paracrine signalling , microbiology and biotechnology , vasoactive , endothelium , endothelial stem cell , function (biology) , biology , chemistry , endocrinology , in vitro , receptor , biochemistry
Some endothelial-derived compounds are able to cross the membrane and regulate the function of other nearby cells. The coronary arteries release endothelial factors and as such mediate paracrine action both on myocardiocytes and smooth muscle cells.Among the endothelial vasoactive substances released from the coronary arteries are Endothelial Derived Relaxing Factor (EDRF), Endothelial Derived Hyperpolarizing Factors (EDHFs), prostaglandins and endothelines 1,2,3 (ET-1, ET-2, ET-3). [...]