Open AccessPrimary amyloidosis presenting intrahepatic cholestasis and fulminant hepatic failure
Author(s) -
Öztürk Ateş,
Kemal Kösemehmetoğlu,
Güneş Güner,
Yusuf Bayraktar
Publication year - 2015
Publication title -
italian journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.134
H-Index - 10
eISSN - 1877-9352
pISSN - 1877-9344
DOI - 10.4081/itjm.2015.593
Subject(s) - medicine , hepatosplenomegaly , cholestasis , fulminant hepatic failure , amyloidosis , gastroenterology , al amyloidosis , abdominal pain , multiple myeloma , pathology , immunoglobulin light chain , immunology , transplantation , disease , antibody , liver transplantation
A 69-year-old man noticed abdominal pain located on right upper quadrant. Physical examination showed hepatosplenomegaly and icteric discoloration of sclera. On evaluation, patient was diagnosed to have hepatic amyloidosis related monoclonal gammopathy of undetermined significance (MGUS) and sinusoidal obstruction syndrome with intrahepatic cholestasis. In this case report we emphasize fulminant hepatic failure due to primer amyloidosis in diagnosed with MGUS patient