Open AccessHypocomplementemic urticarial vasculitis complicated with diffuse alveolar hemorrhage: a case report and review of literature
Author(s) -
Paola Gnerre,
S Buscaglia,
A Cattana,
A Pestarino,
Silvia Marina Ardoino,
Ezio Venturino,
Lionello Parodi
Publication year - 2014
Publication title -
italian journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.134
H-Index - 10
eISSN - 1877-9352
pISSN - 1877-9344
DOI - 10.4081/itjm.2014.155
Subject(s) - medicine , diffuse alveolar hemorrhage , vasculitis , cyclophosphamide , dermatology , dexamethasone , pathology , complication , chemotherapy , disease
Urticarial vasculitis is a small-vessel vasculitis characterized clinically by urticaria and microscopically by leukocytoclastic vasculitis. Hypocomplementemic urticarial vasculitis syndrome is a rare subtype of urticarial vasculitis with organ involvement and persistent, acquired hypocomplementemia. Pulmonary involvement, usually seen as diffuse alveolar damage, is an uncommon complication and a significant cause of morbidity and mortality. Here we present a rare case of hypocomplementemic urticarial vasculitis syndrome complicated by diffuse alveolar damage and describe the beneficial effect of cyclophosphamide-dexamethasone