HIV associated neurocognitive disorders | Zendy

Li Zhou | Zendy; Nitin K. Saksena | Zendy

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HIV associated neurocognitive disorders

Author(s) -

Li Zhou,

Nitin K. Saksena

Publication year - 2013

Publication title -

infectious disease reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.487

H-Index - 17

ISSN - 2036-7449

DOI - 10.4081/idr.2013.s1.e8

Subject(s) - neurocognitive , medicine , human immunodeficiency virus (hiv) , dementia , cognition , antiretroviral therapy , psychiatry , immunology , pathology , viral load , disease

Human immunodeficiency virus type 1 is associated with the development of neurocognitive disorders in many infected individuals, including a broad spectrum of motor impairments and cognitive deficits. Despite extensive research, the pathogenesis of HIV-associated neurocognitive disorders (HAND) is still not clear. This review provides a comprehensive view of HAND, including HIV neuroinvasion, HAND diagnosis and different level of disturbances, influence of highly-active antiretroviral therapy to HIV-associated dementia (HAD), possible pathogenesis of HAD, etc. Together, this review will give a thorough and clear understanding of HAND, especially HAD, which will be vital for future research, diagnosis and treatment

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