Open AccessBrief report on cognitive function and corticosteroid therapy in elderly
Author(s) -
Alberto Castagna,
Giuseppe Coppolino,
Carmen Ruberto,
Giovanni Ruotolo,
Ciro Manzo
Publication year - 2020
Publication title -
geriatric care
Language(s) - English
Resource type - Journals
eISSN - 2465-1397
pISSN - 2465-1109
DOI - 10.4081/gc.2020.8785
Subject(s) - medicine , prednisone , cognition , pathological , corticosteroid , cohort , population , glucocorticoid , physical therapy , psychiatry , environmental health
Glucocorticoids (GCs) are drugs commonly used for the treatment of a great number of acute or chronic pathological conditions. In a cross-sectional study we analyze a cohort of elderly patients treated for at least four weeks with a glucocorticoid (GC), exactly prednisone therapy, for a renal or rheumatological condition pointing out on functional, mental and clinical status. The main purpose was to assess change in cognitive performances. Corticosteroids administration also at low dosage in older subjects could enhance cognitive function. This observation should be proved in larger population and underlying mechanisms studied in deep.