Open AccessCell cycle checkpoints: methods and protocols
Author(s) -
Carlo Alberto Redi
Publication year - 2012
Publication title -
european journal of histochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 42
eISSN - 2038-8306
pISSN - 1121-760X
DOI - 10.4081/ejh.2012.br10
Subject(s) - cyclin , cell cycle , cyclin dependent kinase , microbiology and biotechnology , g2 m dna damage checkpoint , kinase , cell cycle checkpoint , chemistry , chek1 , cell , biology , biochemistry
As it is well known at the end of each cell cycle step there are checkpoints to verify that DNA duplication and segregation (among other events) met every requirements before the cell is allowed to proceed to the next step. Multiple signaling molecules, notably cyclins and the cyclin-dependent kinases (CDKs), play major roles in the cell cycle checkpoint’s control...