Open AccessMalignant eccrine spiradenocylindroma and parotid gland involvement in Brooke Spiegler syndrome
Author(s) -
Giulia Merlo,
Marianna Pesce,
Tiziana Borra,
Ileana Orejuela,
Francesca Pasquali,
Renzo Panizza,
Marco Ghiglione,
Federica Grosso
Publication year - 2022
Publication title -
dermatology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.183
H-Index - 10
eISSN - 2036-7406
pISSN - 2036-7392
DOI - 10.4081/dr.2022.9418
Subject(s) - medicine , pathology , parotid gland , malignant transformation , cylindroma , basal cell carcinoma , adenoma , dermatology , basal cell
Brooke-Spiegler syndrome is a rare disorder, characterized by the development of skin adnexal tumors, including cylindromas, trichoepitheliomas, spiradenomas. Although these neoplasms are benign in most patients, a malignant transformation can rarely occur. Furthermore, an occasional association between cutaneous adnexal tumors and basal cell adenoma as well as adenocarcinoma of the parotid gland has been rarely described, with approximately 20 cases reported. We report a case of BSS presenting with a malignant eccrine spiradenocylindroma, in a patient with previous history of parotid basal cell tumor.