Open AccessPromising 3D <em>in vitro</em> models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer
Author(s) -
Stefania Forciniti,
Marta Cavo,
Ilaria Dando,
Elisa Dalla Pozza,
Marta Palmieri,
Loretta L. del Mercato
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.169
Subject(s) - pancreatic cancer , in vitro , cancer research , tumor microenvironment , cancer , spheroid , medicine , biology , tumor cells , biochemistry
In this study we produced 3D organotypic cultures and spheroids to mimic the complex microenvironment of pancreatic cancer and to test alternative therapeutic strategies.