Open AccessTowards reliable <em>in vitro</em> models – New bi-compartmental platforms for replicating tissue barriers
Author(s) -
L. P. Coppadoro,
Elia Pederzani,
Chiara Foglieni,
Maria Lombardi,
Gianfranco Beniamino Fiore,
Monica Soncini
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.166
Subject(s) - in vitro , pathophysiology , tissue culture , microbiology and biotechnology , cell culture , chemistry , computational biology , biology , medicine , pathology , biochemistry , genetics
In vitro cell cultures represent a widespread methodology for pathophysiology studies with a high benefit/cost ratio. We have developed and are validating TToP, a novel, versatile, and scalable culture system allowing compartmentalized cell/tissue cultures with the aim of mimicking the human pathophysiological microenvironment of tissue barriers.