Open AccessAn osteochondral bio-engineered model to <em>in vitro</em> mimicking osteoarthritis
Author(s) -
Giorgia Cerqueni,
Annachiara Scalzone,
Xiao g Wang,
Caterina Licini,
Kenny Dalgarno,
Ana Marina Ferreira-Duarteunited k,
Piergiorgio Gentile,
M. Mattioli Belmonte
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.162
Subject(s) - osteoarthritis , in vitro , medicine , drug delivery , pathology , biology , materials science , nanotechnology , biochemistry , alternative medicine
To date, treatments of Osteoarthritis are not able to provide the pathology regression. In vitro models are therefore necessary to: i) investigate the mechanisms involved in the disease evolution, ii) identify pharmacological targets, and iii) perform predictive tests for new drug delivery strategies.