Open AccessSuperoxide dismutase 1 (SOD1) and cadmium: a three models approach to the comprehension of its neurotoxic effects
Author(s) -
Federica Bovio,
Barbara Sciandrone,
Chiara Urani,
Paola Fusi,
Matilde Forcella,
Maria Elena Regonesi
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.157
Subject(s) - sod1 , superoxide dismutase , cadmium , caenorhabditis elegans , recombinant dna , chemistry , antioxidant , microbiology and biotechnology , biology , biochemistry , gene , organic chemistry
In three different biological models, the recombinant protein expressed in E. coli, the neuronal cells SH-SY5Y and the nematode Caenorhabditis elegans, cadmium inhibits SOD1 activity without affecting its expression level.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom