Open AccessInk-jet printed chitosan precise patterning for engineered 2D neuronal networks
Author(s) -
Andrea Andolfi,
Pietro Arnaldi,
Donatella Di Lisa,
Sergio Martinoia,
Laura Pastorino
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.148
Subject(s) - micropatterning , chitosan , induced pluripotent stem cell , nanotechnology , materials science , chemistry , embryonic stem cell , biochemistry , gene
The aim of this work was to demonstrate chitosan micropatterning effectiveness to realize spatially guided 2D neuronal networks of primary rat neurons and neurons derived from human induced pluripotent stem cells (h-iNeurons). Morphological characterizations were carried out to validate the formation of a well-defined neuronal networks.