Open AccessA millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies
Author(s) -
Anna Maria Bassi,
Sara Tirendi,
Sonia Scarfı̀,
Mario Passalacqua,
Vanessa Almonti,
Stefania Vernazza
Publication year - 2021
Publication title -
biomedical science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2531-9892
DOI - 10.4081/bse.2021.135
Subject(s) - trabecular meshwork , glaucoma , neuron , apoptosis , cascade , medicine , nanotechnology , neuroscience , biomedical engineering , materials science , ophthalmology , biology , chemistry , biochemistry , chromatography
The aim of this present study is to investigate the role of damaged Trabecular Meshwork (TM) in triggering neuron-like cell apoptosis. Preliminary results showed that stressed TM releases harmful signals to neuron-like cells, suggesting its pivotal role in glaucoma cascade.