Open AccessOne step nucleic acid amplification (OSNA) for detection of lymph node metastasis during robotic radical prostatectomy for prostate cancer: A pilot study
Author(s) -
Ömer Burak Argun,
Panagiotis Mourmouris,
Yeşim Sağlıcan,
Tünkut Doğanca,
Mustafa Bilal Tuna,
Cavit Kerem Kayhan,
Özge Yalçınkaya,
İlter Tüfek,
Halil Kara,
Can Öbek,
Ümit İnce,
Lazaros Tzelves,
Andreas Skolarikos,
Ali Rıza Kural
Publication year - 2022
Publication title -
archivio italiano di urologia andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.429
H-Index - 23
eISSN - 2282-4197
pISSN - 1124-3562
DOI - 10.4081/aiua.2022.3.265
Subject(s) - prostatectomy , medicine , lymph , prostate cancer , lymph node , dissection (medical) , cytokeratin , metastasis , radiology , urology , oncology , pathology , cancer , immunohistochemistry
The OSNA technique is based on reverse transcription loop-mediated DNA amplication for the detection of cytokeratin 19 (CK19) messen-ger RNA (mRNA). The purpose of our paper, which represents the rst study in the literature, is to test the accuracy of this method in the detection of lymph node metastases in patients undergoing robotic radical prostatectomy with lymph node dis-section.