
Effect of green tea catechins in patients with high-grade prostatic intraepithelial neoplasia: Results of a short-term double-blind placebo controlled phase II clinical trial
Author(s) -
Salvatore Micali,
Angelo Territo,
Giacomo Maria Pirola,
N. Ferrari,
Maria Chiara Sighinolfi,
Eugenio Martorana,
Michele Navarra,
Giampaolo Bianchi
Publication year - 2017
Publication title -
archivio italiano di urologia andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.429
H-Index - 23
eISSN - 2282-4197
pISSN - 1124-3562
DOI - 10.4081/aiua.2017.3.197
Subject(s) - medicine , green tea extract , placebo , clinical trial , intraepithelial neoplasia , catechin , prostate cancer , prostate specific antigen , green tea , adverse effect , gastroenterology , cohort , prostate , randomized controlled trial , urology , cancer , pathology , antioxidant , polyphenol , food science , chemistry , biochemistry , alternative medicine
Several studies suggest a protective role of green tea catechins against prostate cancer (PCa). In order to evaluate the efficacy of green tea catechins for chemoprevention of PCa in patients with high-grade prostate intraepithelial neoplasia (HG-PIN) we performed a phase II clinical trial.