Open AccessMalignant melanoma of soft parts with osteoclast-rich giant cells: A rare
Author(s) -
Saumyaranjan Mallick,
Lavleen Singh,
K. D. Anand Rajan,
Meher Chand Sharma,
VK Bansl,
Amit Kumar Dinda
Publication year - 2014
Publication title -
the australasian medical journal
Language(s) - English
Resource type - Journals
ISSN - 1836-1935
DOI - 10.4066/amj.2014.1970
Subject(s) - medicine , immunohistochemistry , giant cell , melanoma , pathology , stromal cell , lesion , osteoclast , abdominal pain , radiology , cancer research , receptor
Malignant melanoma of soft parts (MMSP), first described by Franz M. Enzinger, is a rare tumour of unknown cell origin. We describe a case of a 45-year-old male who presented with a one-year history of abdominal pain, weakness, and anaemia. Computerised tomography enteroclysis showed a mass in the jejunum that was suggestive of a gastrointestinal stromal tumour. An ulceroinfiltrative lesion measuring 6.5 x 4 x 2cm was identified. Microscopy revealed typical features of MMSP with numerous osteoclasts-like giant cells. The diverse histomorphology and immunohistochemical characteristics of this case involving a rare tumour at a rare site is presented.