Open AccessHOXD Antisense Growth-Associated Long Noncoding RNA Promotes Triple-Negative Breast Cancer Progression by Activating Wnt Signaling Pathway
Author(s) -
Chenguang Zhang,
Ying Yang,
Yi Lee,
Xuelaiti Paizula,
Wenting Xu,
Xiuping Wu
Publication year - 2021
Publication title -
journal of breast cancer/journal of breast cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 36
eISSN - 2092-9900
pISSN - 1738-6756
DOI - 10.4048/jbc.2021.24.e24
Subject(s) - wnt signaling pathway , triple negative breast cancer , cancer research , microrna , long non coding rna , competing endogenous rna , breast cancer , rna binding protein , cell growth , rna , biology , signal transduction , cancer , medicine , microbiology and biotechnology , gene , genetics
Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer owing to high heterogeneity, aggressive nature, and lack of treatment options, which has a substantial deleterious effect on patients' lives. HOXD antisense growth-associated long noncoding RNA (lncRNA) (HAGLR) plays tumor-promoting roles in many cancers. In this study, we aimed to explore the role of HAGLR in TNBC.