Open AccessMultiple Symmetric Lipomatosis (Madelung's Disease) Presenting as Bilateral Huge Gynecomastia
Author(s) -
Jae Hoon Jang,
Anbok Lee,
Sun-Hee Han,
Jung Kyu Ryu,
Jeong Yoon Song
Publication year - 2014
Publication title -
journal of breast cancer/journal of breast cancer
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 36
eISSN - 2092-9900
pISSN - 1738-6756
DOI - 10.4048/jbc.2014.17.4.397
Subject(s) - gynecomastia , medicine , lipomatosis , rare disease , liposuction , etiology , mastectomy , disease , surgery , dermatology , radiology , breast cancer , pathology , cancer
Multiple symmetric lipomatosis (MSL), or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and upper body. MSL presenting as bilateral huge gynecomastia is an extremely rare phenomenon. The present report describes a case of MSL in a 66-year-old man. The patients presented with bilateral breast bulging. He had a history of cigarette and alcohol use. His condition was treated with a bilateral nipple-sparing mastectomy. MSL can present as a form of gynecomastia, for its accurate diagnosis and proper treatment of MSL, increasing awareness of the clinical characteristics of the disease is required, especially amongst breast surgeons. Herein, we review the literature and discuss the clinical characteristics, pathology, and surgical treatment of MSL.