Open AccessPotential of <em>Annona muricata</em> L. seed oil: phytochemical and nutritional characterization associated with non-toxicity
Author(s) -
Laíse Cedraz Pinto,
Carolina Oliveira de Souza,
Silvana Alves de Souza,
H. B. da Silva,
R. R. da Silva,
Ana Tereza Cerqueira-Lima,
Tatiane Oliveira Teixeira,
T. M.S. da Silva,
Kelson C. Medeiros,
Milena Lopes Francisco Bittencourt,
Helena Rahy Brandão,
Janice Izabel Druzian,
Adilva S. Conceição,
Mariângela Vieira Lopes,
Camila A. Figueiredo
Publication year - 2018
Publication title -
grasas y aceites
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.384
H-Index - 46
eISSN - 1988-4214
pISSN - 0017-3495
DOI - 10.3989/gya.0777171
Subject(s) - phytochemical , dpph , chemistry , linoleic acid , abts , toxicity , oleic acid , annona muricata , antioxidant , fatty acid , chloroform , food science , high performance liquid chromatography , traditional medicine , chromatography , botany , biology , biochemistry , organic chemistry , medicine
The aim of this study was to evaluate the nutritional quality, phenolic compounds, fatty acid and antioxidant activity in vitro as well as a toxicological screening of A. muricata seed oil in vivo. The chemical composition and quantification of phenolic compounds were determined by the Adolfo Lutz Institute normative. The antioxidant activity was evaluated by DPPH, FRAP and ABTS methods. The oil was extracted by chloroform/ methanol and precipitated crude (AmPtO) and supernatant oils (AmSO) were obtained. The fatty acid profile was evaluated by gas chromatography and total compounds by HPLC-DAD. BALB/C mice received AmPtO and AmSO (0.5 and 1.0mL·Kg-1) for 14 days. Toxicity parameters were assessed. The major fatty acids in the oil were oleic (39.2%) and linoleic (33%). HPLC-DAD suggested the presence of acetogenins (annonacin: 595 [M-H]-), with a greater presence in AmPtO. The AmPtO group showed toxicity, which may be related to the acetogenin content in AmPtO. The AmSO group showed no toxicity and this oil has potential for food or medicinal use.