Open AccessEvaluating an In-House Cell-Based Assay for Detecting Antibodies Against Muscle-Specific Tyrosine Kinase in Myasthenia Gravis
Author(s) -
Min Ju Kim,
Seung Woo Kim,
MinGi Kim,
Young Chul Choi,
Seung Min Kim,
Ha Young Shin
Publication year - 2021
Publication title -
journal of clinical neurology/the journal of clinical neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.208
H-Index - 45
eISSN - 2005-5013
pISSN - 1738-6586
DOI - 10.3988/jcn.2021.17.3.400
Subject(s) - myasthenia gravis , antibody , colocalization , microbiology and biotechnology , cell culture , tyrosine kinase , hek 293 cells , biology , chemistry , medicine , immunology , receptor , genetics
Detecting antibodies against muscle-specific tyrosine kinase (MuSK Abs) is essential for diagnosing myasthenia gravis (MG). We applied an in-house cell-based assay (CBA) to detect MuSK Abs.