Open AccessA Patient with Genetically Confirmed Myoclonus-Dystonia Responded to Anticholinergic Treatment and Improved Spontaneously
Author(s) -
Jae Hyeok Lee,
Chul Hyoung Lyoo,
Myung Sik Lee
Publication year - 2011
Publication title -
journal of clinical neurology/the journal of clinical neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.208
H-Index - 45
eISSN - 2005-5013
pISSN - 1738-6586
DOI - 10.3988/jcn.2011.7.4.231
Subject(s) - myoclonus , dystonia , medicine , deep brain stimulation , trunk , anticholinergic , anesthesia , psychology , pediatrics , psychiatry , biology , ecology , disease , parkinson's disease
The various medical treatments applied to myoclonus-dystonia patients with a mutation of the ε-sarcoglycan gene (SGCE) have not been beneficial in most cases. Most patients experience progressive deterioration or static clinical courses, with only rare cases of spontaneous remission.