Open AccessSynthetic Study Directed toward Derivatives of Biologically Active Indolo[2,3-a]carbazole
Author(s) -
Masanori Somei,
Masako Satô,
Yoshiaki Suzuki,
Fumio Yamada
Publication year - 2010
Publication title -
heterocycles
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.242
H-Index - 64
eISSN - 1881-0942
pISSN - 0385-5414
DOI - 10.3987/com-09-s(s)79
Subject(s) - chemistry , carbazole , biological activity , combinatorial chemistry , stereochemistry , organic chemistry , biochemistry , in vitro
Various derivatives of (6R (*),6aR (*))-6-chloro-6a-hydroxy-5, 6,6a,12-tetrahydroindolo[2,3-a]carbazole-5-one (8) and 6-cyano-5- hydroxyindolo[2,3-a]-carbazole (9) are prepared. Preparations of (6R (*),6aR (*),11aR (*))-6-chloro-11a-cyano-6a-hydroxy- (11) and 12-substituted 6-(Z)-aminomethylidene-5,6,6a, 11,11a,12-hexahydroindolo[2,3-a] carbazole-5-ones (15) are also reported. © 2010 The Japan Institute of Heterocyclic Chemistry Received
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