Applying inappropriate cutoffs leads to misinterpretation of folate status in the US population
Author(s) -
Christine M Pfeiffer,
Maya Sternberg,
Heather C. Hamner,
Krista S. Crider,
David A. Lacher,
Lisa M. Rogers,
Regan L Bailey,
Elizabeth A Yetley
Publication year - 2016
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.116.138529
Subject(s) - medicine , megaloblastic anemia , homocysteine , population , cutoff , anemia , gastroenterology , physiology , environmental health , physics , quantum mechanics
Folate cutoffs for risk of deficiency compared with possible deficiency were originally derived differently (experimental compared with epidemiologic data), and their interpretations are different. The matching of cutoffs derived from one assay with population-based data derived from another assay requires caution.
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